Description
Description:
Exemestane 25mg/ml is a medication formulated as a liquid solution containing exemestane as the active ingredient. Exemestane is an oral aromatase inhibitor used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It is commonly prescribed as adjuvant therapy following surgery or other treatments to reduce the risk of cancer recurrence.
Indications:
Exemestane is indicated for the treatment of hormone receptor-positive breast cancer in postmenopausal women. It is typically used in the following settings:
- Adjuvant Therapy: Exemestane is used as adjuvant treatment following surgery or other primary treatments to reduce the risk of cancer recurrence in postmenopausal women with early-stage breast cancer.
- Metastatic Breast Cancer: Exemestane may also be used for the treatment of advanced or metastatic breast cancer in postmenopausal women who have progressed on other hormonal therapies.
How It Works:
Exemestane belongs to a class of medications known as aromatase inhibitors. It works by inhibiting the enzyme aromatase, which is responsible for converting androgens (male hormones) into estrogen (female hormone) in peripheral tissues, such as fat, muscle, and breast cancer cells. By blocking estrogen production, exemestane reduces estrogen levels in the body, thereby inhibiting the growth of estrogen-sensitive breast cancer cells.
Dosage and Administration:
The dosage of Exemestane 25mg/ml varies depending on the patient’s medical condition, treatment history, and other factors. It is administered orally as directed by a healthcare professional. The recommended dosage for adjuvant treatment of early-stage breast cancer is typically 25 mg taken once daily, preferably after a meal. For metastatic breast cancer, the dosage may be higher, and treatment may continue until disease progression or unacceptable toxicity occurs.
Possible Side Effects:
Common side effects of Exemestane may include:
- Hot Flashes: Exemestane can cause hot flashes or flushing, particularly during the initial weeks of treatment.
- Fatigue: Feeling tired or weak is a common side effect reported by patients taking exemestane.
- Joint Pain: Exemestane may cause joint pain or stiffness, which can affect mobility and quality of life.
- Bone Loss: Long-term use of exemestane may increase the risk of bone loss (osteoporosis) and fractures in postmenopausal women.
- Nausea: Some individuals may experience nausea or gastrointestinal discomfort during treatment with exemestane.
- Headache: Headache is a common side effect reported during treatment with exemestane.
Warnings and Precautions:
- Bone Health: Patients taking exemestane should undergo regular bone density assessments and receive appropriate supplementation or treatment for osteoporosis, if necessary.
- Hormone Replacement Therapy: Exemestane may interfere with the effectiveness of hormone replacement therapy (HRT) and oral contraceptives containing estrogen. Alternative methods of contraception should be used in premenopausal women.
- Liver Function: Liver function tests should be monitored regularly during treatment with exemestane, as it can cause liver toxicity in some individuals.
Exemestane 25mg/ml is a prescription medication used for the treatment of hormone receptor-positive breast cancer in postmenopausal women. Patients should follow their healthcare provider’s instructions regarding dosage, administration, and monitoring for adverse effects. Any concerns or potential side effects should be discussed with a healthcare professional.
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