Description
RoActemra (tocilizumab) is a medication used to treat certain autoimmune and inflammatory diseases. It is a humanized monoclonal antibody that targets the interleukin-6 receptor (IL-6R).
Uses:
RoActemra is used to treat rheumatoid arthritis (RA), juvenile idiopathic arthritis (JIA), giant cell arteritis (GCA), and cytokine release syndrome (CRS) associated with chimeric antigen receptor (CAR) T cell therapy. It can be used alone or in combination with other medications.
Storage Conditions:
RoActemra should be stored at refrigerator temperature (2°C to 8°C). It should be protected from light and should not be frozen.
Mechanism of Action:
RoActemra works by blocking the activity of IL-6, a protein that plays a role in inflammation and autoimmunity. This reduces the inflammatory response and can alleviate the symptoms associated with certain autoimmune and inflammatory diseases.
HOW TO USE:
RoActemra is given as a subcutaneous injection or an intravenous infusion in a healthcare setting. The dosage may vary depending on the individual’s weight, age, and medical condition. Patients should not change their dosage or stop taking the medication without first consulting with a healthcare provider.
Precautions:
• RoActemra may increase the risk of infections, including serious infections. Patients should be closely monitored for signs of infection while taking this medication.
• Patients with a history of hepatitis B virus (HBV) infection should be screened before starting treatment with RoActemra.
• Patients who have recently received a live vaccine should not start treatment with RoActemra until two weeks after vaccination.
Drug Interactions:
RoActemra may interact with other medications that suppress the immune system or increase the risk of infection. Patients should inform their healthcare provider of all medications that they are taking while using RoActemra.
Contraindications:
RoActemra is contraindicated in patients with a known hypersensitivity to tocilizumab or any of the ingredients in the medication. It should not be used in patients with active infections or a history of tuberculosis.
Overdose:
In the event of an overdose, patients should seek immediate medical attention. Symptoms may include headache, rash, and fever.
Adverse Reactions:
Common adverse reactions associated with the use of RoActemra include infections, infusion reactions, and increased liver function tests. Patients should contact their healthcare provider if they experience any unusual reactions while taking RoActemra.
In conclusion, RoActemra is a medication used to treat certain autoimmune and inflammatory diseases. It works by blocking the activity of IL-6, a protein that plays a role in inflammation and autoimmunity. Patients should take the medication exactly as prescribed by a healthcare provider and should be monitored for signs of infection. Adverse reactions such as infections, infusion reactions, and increased liver function tests can occur, and patients should contact their healthcare provider if any unusual reactions occur. It is contraindicated in patients with a known hypersensitivity to tocilizumab or any of the ingredients in the medication.
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