Description
Verquvo (vericiguat) is a prescription medication used to treat adults with heart failure with reduced ejection fraction. It is taken in combination with other medications that are already being used to treat heart failure. Verquvo belongs to a class of drugs called guanylate cyclase stimulators.
Uses:
Verquvo is indicated for the treatment of heart failure with reduced ejection fraction (HFrEF) in adults who have recently been hospitalized for worsening heart failure or have chronic heart failure. It is used in combination with other medications used to treat heart failure.
Storage Conditions:
Verquvo should be stored at room temperature and protected from light and moisture. It should be kept out of reach of children.
Mechanism of Action:
Verquvo works by stimulating the production of cyclic guanosine monophosphate (cGMP) by activating the soluble guanylate cyclase enzyme. This helps to relax the blood vessels, increase blood flow, and reduce inflammation in the body. As a result, the heart can pump blood more efficiently, and symptoms of heart failure may improve.
HOW TO USE:
Verquvo is usually taken orally, one tablet once daily, with or without food. It is important to follow the dosing instructions provided by your doctor. If a dose is missed, it should be taken as soon as remembered, but not to take the missed dose if it is close to the next scheduled dose. Do not take more than one tablet per day.
Precautions:
Before taking Verquvo, inform your doctor if you are pregnant or breastfeeding, have low blood pressure, kidney or liver problems, or are taking other medications. Verquvo may cause dizziness and low blood pressure, especially during the first few days of treatment, therefore, avoid driving or operating heavy machinery until you know how this medicine affects you.
Drug Interactions:
Verquvo may interact with certain medications such as rifampin, carbamazepine, St. John’s Wort, and phenobarbital. It is important to inform your doctor of all the medications you are currently taking, including over-the-counter drugs and supplements.
Contraindications:
Verquvo is contraindicated in patients who are hypersensitive or allergic to vericiguat or any of its components.
Overdose:
If you suspect an overdose of Verquvo, seek medical attention immediately. Symptoms of an overdose may include headache, dizziness, nausea, vomiting, and diarrhea.
Adverse Reactions:
Common side effects of Verquvo may include low blood pressure, anemia, cough, headache, and diarrhea. These side effects usually resolve within a few days of starting the medication or with dose adjustments. Serious adverse reactions, such as angioedema, can occur with this medication. If you experience any signs or symptoms of an allergic reaction, including swelling of the face or tongue, difficulty breathing, or rash, seek medical attention immediately.
In conclusion, Verquvo is an effective medication for the treatment of heart failure with reduced ejection fraction in adults. It should be taken under the guidance of a healthcare professional, and used in combination with other medications that are used to treat heart failure. It is essential to follow the dosing instructions provided by the doctor, avoid activities that require alertness until the effect of the medicine is known and promptly inform your doctor of any adverse effects you may experience.
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