Description
Calcort (deflazacort) is a medication that is used to treat a variety of conditions that cause inflammation in the body. It is a type of steroid that works by reducing the production of the chemicals that cause inflammation. Calcort is available in tablet form and should only be used under the supervision of a medical professional.
Uses
Calcort is primarily used to treat conditions that cause inflammation, such as arthritis, asthma, and multiple sclerosis. It is also sometimes used to suppress the immune system in transplant patients and treat certain types of cancer. However, it is important to note that Calcort is not a cure for any of these conditions.
Storage Conditions
Calcort should be stored at room temperature, away from direct sunlight and moisture. It should also be kept out of reach of children and pets. Unused or expired medication should be disposed of properly according to local regulations.
Mechanism of Action
Calcort is a corticosteroid that works by reducing the production of chemicals that cause inflammation in the body. It binds to glucocorticoid receptors and regulates gene transcription, resulting in a reduction in the transcription of genes that are responsible for inflammation. Calcort also suppresses the activity of the immune system, which is responsible for the inflammation associated with autoimmune conditions.
HOW TO USE
Calcort should be taken orally, with or without food, as directed by a medical professional. The dose may vary depending on the individual’s medical condition and response to treatment. It is important to follow the prescribed dosing schedule and not to take more or less than recommended. Calcort tablets should not be crushed, chewed, or broken.
Precautions
Before taking Calcort, individuals should inform their medical provider of any medical conditions they have, including liver or kidney disease, diabetes, and high blood pressure. Calcort may cause dizziness and drowsiness, and individuals should avoid driving or operating heavy machinery until they know how the medication affects them. Long-term use of Calcort may also increase the risk of certain side effects, including osteoporosis, cataracts, and infections. Thus, it is important to follow-up with medical providers for regular check-ups, and monitoring of potential side effects.
Drug Interactions
Calcort may interact with other medications, including medications used to treat diabetes, blood thinners, and nonsteroidal anti-inflammatory drugs (NSAIDs). Individuals should inform their medical provider of all medications, including over-the-counter drugs and supplements, that they are taking before starting treatment with Calcort.
Contraindications
Calcort is contraindicated in individuals who have a hypersensitivity to deflazacort or any of its components. Individuals with serious infections or untreated infections should also avoid taking Calcort. Additionally, it is advised that individuals avoid taking live vaccines while using Calcort.
Overdose
In the event of an overdose, individuals should seek immediate medical attention. An overdose may result in symptoms such as weakness, fatigue, and increased blood pressure.
Adverse Reactions
Calcort may cause several adverse reactions, including dizziness, headache, nausea, and vomiting. More serious side effects may include changes in mood, difficulty sleeping, and increased appetite. Long-term use of Calcort may also increase the risk of osteoporosis, cataracts, and infections. Individuals who experience any of these side effects should inform their medical provider immediately. Calcort may also cause withdrawal symptoms when it is stopped abruptly. Symptoms may include fatigue, joint pain and stiffness, and muscle weakness. Thus, medication should not be stopped abruptly, but rather slowly tapered off under the supervision of a medical professional.
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