Description
Austedo (deutetrabenazine) is a medication that is used to treat involuntary movements that are caused by conditions such as Huntington’s chorea and tardive dyskinesia. It is a central nervous system depressant that works by lowering the levels of dopamine, a neurotransmitter that is responsible for regulating movement. Austedo is available in tablet form and should only be used under the supervision of a medical professional.
Uses
Austedo is primarily used to treat the involuntary movements that are associated with Huntington’s chorea and tardive dyskinesia. It is also sometimes used to treat other conditions that cause similar symptoms, such as Tourette’s disorder. However, it is important to note that Austedo is not a cure for any of these disorders.
Storage Conditions
Austedo should be stored at room temperature, away from direct sunlight and moisture. It should also be kept out of reach of children and pets. Unused or expired medication should be disposed of properly according to local regulations.
Mechanism of Action
Austedo works by selectively inhibiting the activity of the dopamine transporter, which reduces the levels of dopamine in the brain. By doing so, it helps to control the involuntary movements that are associated with Huntington’s chorea and tardive dyskinesia. However, the exact mechanism of action of Austedo is not fully understood.
HOW TO USE
Austedo should be taken orally, with or without food, as directed by a medical professional. The dose may vary depending on the individual’s medical condition and response to treatment. It is important to follow the prescribed dosing schedule and not to take more or less than recommended. Austedo tablets should not be crushed, chewed, or broken.
Precautions
Before taking Austedo, individuals should inform their medical provider if they have a history of depression, suicidal thoughts, or drug and alcohol abuse. Austedo may cause drowsiness, dizziness, and other side effects that can affect the ability to perform tasks that require alertness. As such, individuals should avoid driving or operating heavy machinery until they know how the medication affects them. Austedo should also be used with caution in individuals with liver or kidney disease, as these conditions can affect the way the medication is metabolized.
Drug Interactions
Austedo may interact with other medications, including antidepressants, antihistamines, and other drugs that affect the levels of dopamine in the brain. Individuals should inform their medical provider of all medications, including over-the-counter drugs and supplements, that they are taking before starting treatment with Austedo.
Contraindications
Austedo is contraindicated in individuals who have a history of hypersensitivity to deutetrabenazine or any of its components. It should not be taken with monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping their use.
Overdose
In the event of an overdose, individuals should seek immediate medical attention. Symptoms of an overdose may include drowsiness, dizziness, fainting, and agitation.
Adverse Reactions
Austedo may cause several adverse reactions, including drowsiness, dizziness, headache, dry mouth, nausea, and vomiting. More serious side effects may include depression, suicidal thoughts, and changes in heart rate and blood pressure. Individuals who experience any of these side effects should inform their medical provider immediately. Austedo may also cause a potentially life-threatening condition called serotonin syndrome when taken with other medications that affect serotonin levels in the brain. Symptoms include fever, seizures, and confusion.
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