Experts Report Surge in Mucormycosis Cases in India: 8,500 New Cases in Two Weeks Linked to Steroid Treatment for COVID-19

Misfortunes never come singly!
Recently, there has been a rapid increase in cases of mycosis infection among COVID-19 patients in India.
As of May 22, 8,848 cases of Mucor infection had been reported across India and 212 people had died, according to figures cited by Indian media.
Just two weeks ago (9 May), only about 300 people in India had been infected with the disease.

According to reports by India Today, NDTV and other Indian media, the medical community in India has yet to reach a final conclusion on the cause of the infection. However, doctors who collected patient data found that most of the infected patients were male, had used steroids during Coronavirus treatment, and most of them had underlying diabetes.

Dr. Vinod Kumar Paul, a medical expert and member of the Indian think tank NITI Aayog, said today (May 22) that the surge in cases of mycormyosis can be attributed to the disproportionate use of steroids in the treatment of COVID-19 patients.

Earlier, India’s Ministry of Health reiterated the importance of “strict adherence” to infection prevention and control practices and urged all regions to strictly control the spread of trichomycosis in hospitals.
Several Indian states, including Rajasthan, Uttar Pradesh, Orissa and Gujarat, have declared Mucormycosis a statutory epidemic.

Screenshot of the report showing more than 8,800 cases of mycosis in India

Immunity low population, easy to infect mycosis

According to Indian doctors and specialists, mucormycosis (Black Fungus) as the “epidemic” of epidemic, by “hairy mould fungi that exist in the natural environment, its symptoms as headache, nasal bleeding, coughing up blood, facial numbness and swelling, blurred vision, breathing difficulties, severe cases may also cause maxilla damage and even blindness.

Experts said Mucormycosis usually “does not pose a significant threat” to people with normal immune systems, but some people are more vulnerable because they have been taking immunosuppressant drugs for a long time for health problems and are less able to fight pathogens in the environment.

Mucormycosis mainly affects arteries and blood vessels, causing thrombosis and necrosis, vision problems, chest pain and breathing difficulties.
In severe cases, the mortality rate of Mucormycosis exceeds 50%.

The treatment of trichomycosis needs to race against time and adopt a multi-pronged approach.
Once a fungal lesion is diagnosed, surgical volume reduction, such as orbital resection or intracranial decompression, must be performed immediately to remove all fungus and necrotic tissue;
In the meantime, patients are given daily intravenous injections of anti-fungal drugs for eight weeks.

“It (Mucormycosis) is everywhere, in the soil and air, even in the noses and mucus of healthy people.
Dr. Akshay Nair, an ophthalmologist in Mumbai, said the body’s defenses keep Mucor out, but when the immune system is weakened, the fungus can take advantage.

The Indian Express counted several conditions that lower a person’s immune system: diabetes, steroid use, hematological malignancies, immunosuppressant use, excessive iron or ferriamine use, trauma, burns and malnutrition.

A patient with Mucormycosis after surgery, pictured from India

There were 8,848 cases of Mucormycosis infection and there was a shortage of drugs

The total number of cases has reached 8,848 and 212 people have died, with 2,281 cases in Gujarat, the worst-hit state, the minister said Monday.
Just two weeks ago (9 May), only about 300 people in India had been infected with the disease.

Guda added on Twitter that the government had sent more than 23,000 vials of key drugs for treatment to the affected states “following a detailed review of the rising number of infections everywhere” in light of the rapid increase in cases of Mucormycosis.

Earlier, the Ministry of Health reiterated the importance of “strict adherence” to infection prevention and control practices, requiring all regions to strictly control the spread of the disease in hospitals and declare it a statutory epidemic.
Indian Prime Minister Narendra Modi also stressed that Mucormycosis is a life-threatening fungal infection and all measures must be taken to prevent it during an online meeting with some of the frontline health care workers on Tuesday.

As of now, Rajasthan, Uttar Pradesh, Orissa, Gujarat and many other states have declared Mucormycosis a statutory epidemic.

Tweets screenshots

Separately, the BBC (BBC) reported on the 23rd that the emergence of cases of Mucor infection has added to the overcrowding of medical resources across India due to the COVID-19.

At a 1,100-bed state hospital in the central Indian city of Indore, the number of patients infected with Mucor had jumped from eight a week earlier to 185 on Tuesday evening.
Dr VP Pandey, the hospital’s medical director, told the BBC that more than 80 per cent of these patients required immediate surgery.

Dr. Pandey said the hospital has set up 11 wards with a total of 200 beds to treat patients with Mucor.
He said: “The spike in the number of patients was absolutely unexpected.
We’ve only seen one or two cases in the past year.”

He estimates that Indore alone has at least 400 patients.
“Currently, Mucor infections are more challenging than Novel Coronavirus.
If patients do not receive prompt and proper treatment, the mortality rate can be as high as 94 percent.
Treatment is expensive and medicines are in short supply.”

The Times of India reported on Wednesday that hospitals across India were experiencing shortages of the antifungal drug amphotericin B.

Screenshots of a shortage of mycosis drugs in India

Use of steroids to treat coronavirus may cause increase in cases, Indian expert says

At present, the medical community in India has not reached a conclusion about the cause of the infection.
But some doctors say the use of steroid drugs to treat patients with severe COVID-19 may be one reason for the surge in cases of mycosis, as the drugs can reduce immunity.

Dr Pandey, from the Indian city of Indore, told the BBC he had collected data from 201 patients at four hospitals in the city.

The patients, mostly men, appear to have developed symptoms of infection within 12 to 18 days of recovering from COVID-19, Dr. Pandey said.
Most of them had used steroids during Coronavirus treatment and all had underlying medical conditions, mainly diabetes.

The BBC cited two other studies by doctors in India: one that looked at more than 100 patients with Mucormycosis, 79 of whom were men, and 83 with diabetes;
Another study looked at 45 patients with mycosis, all of whom had diabetes.
“None of the patients with Mucormycosis have normal blood sugar.”
“Akshay Nayar, an Indian ophthalmologist, told the BBC.

Dr. Vinod Kumar Paul, a medical expert, said the spike in Mucor cases can be attributed to the disproportionate use of steroids in the treatment of COVID-19 patients at a press conference held by NITI Aayog, an Indian think tank, on Wednesday.

A doctor is diagnosing a patient with mycosis. Photo taken in print

Meanwhile, medical experts in India have also suggested that the government should look into other reasons behind the surge in cases of Mucor in parts of the country.

Professor Giridhar Babu, head of life process epidemiology at the Public Health Foundation of India, said: “There are several hypotheses, but the most likely is that it is multifactorial in nature: perhaps the availability of medical oxygen, or the presence of comorbid diseases.”

Two weeks ago, Professor K. Srinath Reddy, chairman of the Public Health Foundation of India, said in an interview that the recent spike in cases of the disease could be caused by inhalation of contaminated water.
“More patients need oxygen this time,” he said at the time.
Many patients use oxygen concentrators at home, and if the water is slightly contaminated, there is a risk of fungal infection, especially for those with weakened immune systems.”

In addition, Mucor exists on wet surfaces, so “patients should make sure the humidifier is waterproof when receiving oxygen support (to prevent the growth of the fungus),” Maffat, head of the department of otolaryngology at a public hospital in Mumbai, warned.

“Estrogen” Levels in Women: 5 Common Indicators to Monitor and Self-Check

Foreword: “woman 40 tofu dreg leucorrhea”, looks excessive and grandiose words, but in fact there is a certain truth, a woman in the past 40 years old, a whole foot has already stepped into the female menopause.

Many people say that the age of 40 is a hurdle for women, but it is true that women age more rapidly as they reach their 40s and their body becomes less resistant to aging.
It’s very easy to get sick.
Therefore, it is very important for a woman to take good care of her body after she is over 40.

The key reason why women age at an accelerated rate in their 40s is that the body produces too little estrogen, so women must keep an eye on estrogen supplements beyond their 40s.

One, “estrogen” more adequate woman, there may be 5 common points, control self check

  1. Be in good shape

Women with a good uterus tend to look better.
If the body’s estrogen secretes everything is normal, can appear department of gynaecology disease is caused hard, because the relativity of the female body’s metabolism working ability is stronger, and the probability of obesity is very rare commonly.

A lot of women in order to better shape and stronger weight loss, especially after giving birth to a child, this kind of body fat is difficult to manipulate, there are a lot of women for this kind of situation to apply a lot of weight loss methods, but there is no actual effect.

Sudoming out of shape after the age of 30 is actually endocrine related.
Endocrine imbalance can contribute to obesity.

If the female body secretes enough estrogen, so even after 40 years old, the woman still can maintain acme body shape.

  1. Smooth skin

The female body is full of estrogen and the endocrine function will be normal. Under such a condition, the cavity, uterus and ovaries will be healthy, and the endotoxin in the skin will be reasonably discharged out of the body, making the skin look bright and smooth.

But with the increase of age, the estrogen level in the female body will be lower and lower, which will reduce the body’s ovaries, and then make the skin difficult.

  1. Sleep well

If the female nocturnal morpheus is high, make clear estrogen secretes abundant, it is the mark that body body and mind are healthy.

Many women’s ovaries decrease during the whole process of improving their age, and the body ages significantly. After suffering harm, the key performance is the reduction of the body’s estrogen level, and the key harm is poor sleep quality at night and sleepless nights.

If there is this kind of insomnia, we must be careful about the secretion of estrogen, and estrogen levels are higher, all the nerve function is normal, women sleep at night will be higher.

4, menstruation is normal and regular

Adequate secretion of estrogen indicates that the uterus, ovary and cavity function are all normal, and the menstrual period will be more regular and more timely. It is not easy to have the problem of less menstrual volume or reduced menstrual cycle, and the menstrual pain will be reduced.

  1. Be in good spirits

Estrogen can all normal secretion, mental outlook will be better and better.

If the female is secreted not enough, can cause action of a lot of human body organs to reduce likely, produce even endocrine disorder main expression, the mental outlook below the harm that endocrine nerve function is disorderly drops.
If energetic glamour is abundant, make clear endocrine is smooth, female estrogen secretes is relatively abundant.

Two, if estrogen is insufficient, how to supplement estrogen?

Eat more legumes and legumes

Eating more soy, large black beans and legumes can balance the body’s estrogen. When the body’s estrogen is too low, large black beans, soy or legumes will boost it.

Royal jelly

Royal jelly with pure natural estrogen, in the kingdom of honey peak, only the queen bee can eat royal jelly, and its service life is 5-6 times that of the general worker bee, she shoulders the burden of creating bees.

Must maintain a high level of estrogen nutrients, people’s respect for pure honey has a long history.

Women often eat royal jelly can improve endocrine and promote estrogen levels.
But hint even a bit, the female that has uterine tumour forbids to eat pure honey and royal jelly.

raisins

Raisins are a kind of food that many eaters like to eat very much. It is also very common in daily life. Girls can eat more raisins in daily life.

Because it can not only have the effect of anti-oxidation, but also reasonable to avoid the deposition of melanin, which contains rich and colorful nutritional elements, can also inhibit the outflow of estrogen.

Therefore, in daily life, people can buy some raisins and eat more when they are free. It is a kind of food that can make you permanent in youth.

Summary: the woman supplements estrogen, besides paying attention to reasonable diet, still need to cultivate a good way of life, do not stay up late, soon sit, prevent obesity, often exercise the body, so physical and mental health and beautiful will be with you for life.

Can Women Take Vitamin B2 Daily? Three Significant Changes to Expect

Guide language: vitamin no matter to everybody’s body growth and development, or maintain a healthy body character, it is very key, accordingly, this also lets a lot of people in daily life, take the vitamin that oneself is filled very seriously.

In fact, many food ingredients in our daily consumption will contain a certain amount of vitamins. As long as we pay more attention to our daily diet and eat it often, it can also supplement the nutrients needed by the body.

01
One, can the female take vitamin B2 everyday?
What will happen to your body?
3 big changes you’re likely to love!
1, anti-aging

It is believed that appearance is the pursuit of every woman, they are looking forward to their own youth, but many women are chilling, to a certain age still can not resist the impression of time left.

This has led many women to develop the habit of taking a daily vitamin B2 supplement, which actually has a certain anti-aging effect, since vitamin B2 can boost the body’s protein synthesis once it enters the body.

In addition, after vitamin B2 enters the human body, it will also have the inhibitory effect on free radicals in the body, which can be said to have a very good effect on delaying aging.

  1. Maintain skin elasticity and clean face

The skin is elastic, the face is clean also is a kind of expression that the woman is young, many women can buy a few skin care products commonly, let the face looks more delicate.

But because the quality of many skin care products is not qualified, so many women have facial allergy symptoms after use, so women can choose to eat some vitamin B2 at this time.

After vitamin B2 enters the human body, there is a kind of effect that speeds up the basic metabolism, the waste that can deposit the skin surface place more quickly and toxin discharge comes out, also having the effect of anti-wrinkle additionally.

  1. Prevent and reduce hair loss

If a person often fill vitamin B2, will also have a very good tonic effect on the hair, some very easy to lose hair women, can eat a piece of vitamin B2 every day in daily life, because vitamin B2 this kind of material after entering the body.

Can promote the basic metabolism of human body, be opposite additionally element of a few nutrition, for example the metabolism of albumen, iron has very good auxiliary effect, can prevent reasonably and reduce the condition that drop hair.

02
Can I take vitamin B2 daily?
The answer is OK, because be in the heart of a lot of people, think is medicine 3 minutes poison, if often take, can bring about a few harm to human body as far as possible.

But vitamin B2 is different, and this kind of medicine can be often taken, because vitamin B2 is not like other drugs, just a water-soluble vitamin material, the body is easy to absorb.

In addition, some substances that should not be stored in the body will be excreted in the urine, so it is OK to take vitamin B2 every day, and there will be no impact on human health.

Conclusion: Finally, I would like to remind you that in general, as long as you choose the right diet in your daily life, you can supplement vitamin B2 for your body.
However, the body is not deficient in vitamin B2 people do not need to deliberately supplement.

Only in the case of lack of vitamin B2 in the body, it should be filled with vitamin B2, in addition to first let the doctor check their own physical conditions, under the specific guidance of the doctor to take medicine, in order to prevent unnecessary harm to the body.

Can Kidney Function Be Restored? Here’s What You Need to Know

The development of chronic kidney disease is divided into four stages, from early to late stage, according to the high and low glomerular filtration rate can be divided into: renal inflammatory reaction stage, renal decompensation stage, renal failure stage, uremia.
Kidneys’ ability to heal varies with each stage, so the chances of healing vary.

Doctors support kidney health.
Doctor supports kidneys healthy.

The first two periods, mainly by judging the degree of damage to kidney cells such as the glomerulus to judge, is to see the recovery ability, generally at this stage, the inflammatory response is less severe, the kidney damage is more mild, the pathology is less severe nephropathy type, timely treatment can basically stabilize the recovery.
At the end stage, kidney inflammation is severe, resulting in more serious damage to kidney cells such as glomerulus, more than half of the fibrosis, sclerosis, substantial changes in renal function, leading to a series of symptoms, serious condition.
At this time, complete recovery after treatment is difficult.

In China, only 1%-2% of the more than 100 million people with kidney disease will progress to uremia, and most of the remaining patients will remain in the stage of renal insufficiency.
It is not easy to maintain an illness in one stage for a long time.

Renal function is difficult to reverse, but to delay the further deterioration of the disease, reverse the situation toward uremia operability is very strong.
To delay the disease, there are two points that kidney friends should pay attention to:

Control symptoms smoothly

Urine and blood test (complete blood count)Urine and blood test (complete

In the early stage, proteinuria, edema, hematuria are the main methods to control inflammation. In the late stage, in addition to proteinuria, hypertension, hyperlipidemia, electrolyte related indicators, anemia are the main ones. In addition, there are high incidence of complications including cardiovascular disease, renal bone disease and so on.

These symptoms are often the “behind the scenes” to push the deterioration of kidney function. When the symptoms and the factors that affect them stabilize, so does overall kidney function.

Increase the importance of long-term review

The doctor gave his patient blood pressure

Only pay attention to the treatment but ignore the examination is long-term kidney disease treatment process taboo.
Many people may have seen this sentence “a hospital to say what symptoms, the doctor must say to do a check to see”, so some people resist the check.
But for patients with kidney disease, has been clear after the beginning of treatment, the inspection project is also very clear, do not have too strong psychological burden.

And kidney disease some key indicators, such as proteinuria, serum creatinine, blood pressure, hemoglobin and so on all is to know the condition changes will check and review of the project is given priority to with “lean”, namely accurate check the reaction of renal function index, change numerous for brief, more accurate understanding of the condition changes directly, not a lot of comprehensive review, so the check or renal, more secure.

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