Description
Description: Alecensa is a medication used in the treatment of a specific type of non-small cell lung cancer (NSCLC) known as anaplastic lymphoma kinase (ALK)-positive metastatic NSCLC. Manufactured by Roche Holding AG, each capsule contains 150 milligrams of the active ingredient Alectinib.
Indications: Alecensa (Alectinib) is indicated for the treatment of patients with ALK-positive metastatic NSCLC who have progressed on or are intolerant to crizotinib.
Mechanism of Action: Alectinib is a tyrosine kinase inhibitor that works by selectively inhibiting the activity of the ALK protein, which is involved in the growth and spread of cancer cells in ALK-positive NSCLC. By inhibiting ALK activity, Alectinib helps slow down or stop the growth of cancer cells and may shrink tumors.
Administration: Alecensa is administered orally in the form of capsules. The recommended dosage and duration of treatment may vary depending on individual patient factors, disease stage, and response to therapy. It is essential to follow the prescribed dosage and administration instructions provided by a healthcare provider.
Dosage and Treatment Plan: The typical dosage of Alecensa (Alectinib) for ALK-positive metastatic NSCLC is 600 milligrams (four capsules of 150 mg) taken orally twice daily with food. The treatment may continue until disease progression or unacceptable toxicity occurs.
Side Effects: Common side effects associated with Alecensa (Alectinib) may include fatigue, constipation, muscle pain, peripheral edema, and cough. Other potential side effects may include liver enzyme elevation, respiratory issues, and vision problems. It is essential to report any adverse reactions to a healthcare provider.
Precautions:
- Alecensa should be used with caution in patients with pre-existing liver or kidney impairment.
- It may interact with other medications, so it’s crucial to inform the healthcare provider about all current medications, including over-the-counter drugs and supplements.
- Pregnant women should avoid using Alecensa, as it may harm the fetus. Effective contraception should be used during treatment and for some time after discontinuation.
Consultation with a Healthcare Provider: Before starting treatment with Alecensa (Alectinib), individuals should consult with a healthcare provider or qualified oncologist. They can provide guidance on proper usage, dosage, and potential risks associated with the medication. Regular monitoring and evaluation are essential to ensure safety and efficacy during treatment.
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