Description
Description:
Aluvia is a medication containing a combination of two antiretroviral drugs, lopinavir, and ritonavir. It is primarily used for the treatment of human immunodeficiency virus (HIV) infection in adults and pediatric patients aged 14 days and older. Lopinavir and ritonavir work together to inhibit the replication of HIV, thereby reducing the viral load and slowing down the progression of HIV disease.
Indications:
Aluvia is indicated for the treatment of HIV-1 infection in combination with other antiretroviral agents. It is used in both treatment-naive and treatment-experienced patients as part of a multidrug regimen known as highly active antiretroviral therapy (HAART) or combination antiretroviral therapy (cART).
Mechanism of Action:
Lopinavir and ritonavir belong to a class of drugs known as protease inhibitors. They work by inhibiting the activity of the HIV protease enzyme, which is essential for the cleavage of viral polyproteins into functional proteins required for viral replication. By blocking protease activity, lopinavir and ritonavir prevent the formation of mature, infectious HIV virions.
Dosage and Administration:
The recommended dosage of Aluvia may vary depending on factors such as the patient’s weight, age, renal function, and previous treatment history. It is typically administered orally as tablets, with the usual adult dose being one tablet (lopinavir 200mg/ritonavir 50mg) taken twice daily with food. The dosage regimen for pediatric patients is based on body weight and should be determined by a healthcare professional.
Side Effects:
Common side effects of Aluvia may include diarrhea, nausea, vomiting, abdominal pain, fatigue, and headache. Some individuals may experience more severe side effects, such as liver toxicity, pancreatitis, or changes in blood lipid levels. Patients should be monitored regularly for signs of adverse reactions during treatment.
Precautions:
Aluvia should be used with caution in patients with certain medical conditions, such as liver or kidney impairment, pancreatitis, or cardiovascular disease. It may interact with other medications, so patients should inform their healthcare provider about all medications they are taking before starting Aluvia treatment. Pregnant or breastfeeding women should consult their healthcare provider before using Aluvia.
Manufacturer:
Aluvia is manufactured by Abbott India Ltd., a leading pharmaceutical company committed to improving healthcare outcomes through the development of innovative medications and healthcare solutions. Abbott India Ltd. adheres to stringent quality standards and manufacturing practices to ensure the safety and efficacy of its products.
Aluvia provides an effective treatment option for individuals living with HIV infection, helping to suppress viral replication and maintain immune function. However, it should only be used under the supervision of a qualified healthcare professional and in accordance with applicable laws and regulations. The information provided here is for educational purposes only and should not be construed as medical advice.
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