Description
Description:
Bortenat is a medication used in the treatment of certain types of cancers, including multiple myeloma and mantle cell lymphoma. It contains the active ingredient bortezomib, which belongs to a class of medications called proteasome inhibitors. Each vial of Bortenat contains 2 mg of bortezomib.
Indications:
Bortenat is indicated for the treatment of:
- Multiple myeloma: It is used in combination with other medications for the treatment of multiple myeloma, a type of cancer that affects plasma cells in the bone marrow.
- Mantle cell lymphoma: Bortenat is used as a single agent for the treatment of mantle cell lymphoma, a type of non-Hodgkin lymphoma.
Mechanism of Action:
Bortezomib works by inhibiting the proteasome, a complex of enzymes in cells that play a role in protein degradation. By blocking the proteasome, bortezomib disrupts the normal regulatory mechanisms within cells, leading to the accumulation of proteins and ultimately triggering cell death in cancer cells.
Administration:
Bortenat is administered by injection into a vein (intravenous infusion) under the supervision of a healthcare professional. The dosage and frequency of administration may vary depending on the patient’s medical condition, response to treatment, and other factors.
Dosage:
The recommended dosage of Bortenat may vary depending on the specific cancer being treated, the patient’s overall health, and other factors. It is important to follow the dosage regimen prescribed by a healthcare provider.
Side Effects:
Common side effects of Bortenat may include:
- Nausea
- Vomiting
- Diarrhea
- Fatigue
- Weakness
- Fever
- Constipation
- Peripheral neuropathy (numbness or tingling in the hands or feet)
- Decreased appetite
- Low blood cell counts (anemia, thrombocytopenia, neutropenia)
Contraindications:
Bortenat is contraindicated in patients with a known hypersensitivity to bortezomib or any other ingredients in the formulation. It should not be used in patients with severe liver impairment or severe kidney impairment.
Storage:
Bortenat should be stored at room temperature (20°C to 25°C) in its original packaging, protected from light and moisture. Do not freeze. Keep out of reach of children and pets.
Prescription Required:
Bortenat is a prescription medication, and its use should be supervised by a qualified healthcare professional.
Note:
This medication description provides only general information about Bortenat and should not be used as a substitute for professional medical advice. Always consult a healthcare professional for guidance on the appropriate use, dosage, and potential risks and benefits of Bortenat in your specific situation.
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