Description
Description:
CA ATRA is a medication manufactured by Bryogen Pharmaceuticals Ltd. It contains the active ingredient Tretinoin, also known as All Trans Retinoic Acid. Each capsule of CA ATRA typically contains 10 mg of Tretinoin.
Active Ingredient:
Tretinoin: Tretinoin is a derivative of Vitamin A and belongs to the class of retinoids. It is primarily used topically in the treatment of acne, but in the case of CA ATRA, it is administered orally. Tretinoin is commonly used in the treatment of acute promyelocytic leukemia (APL), a type of cancer affecting white blood cells. It works by inducing the differentiation of immature promyelocytes into mature cells, leading to the remission of APL.
Manufacturer:
Bryogen Pharmaceuticals Ltd.: Bryogen Pharmaceuticals is the manufacturer of CA ATRA. They are a pharmaceutical company known for producing high-quality medications and adhering to strict quality standards.
Indications:
CA ATRA, containing Tretinoin, is primarily indicated for the treatment of acute promyelocytic leukemia (APL), a subtype of acute myeloid leukemia (AML). It is used as part of a combination therapy regimen, often in combination with chemotherapy agents such as arsenic trioxide, to induce remission in patients with APL. CA ATRA works by promoting the differentiation of abnormal promyelocytes into mature white blood cells, leading to a reduction in leukemia cell population and improvement in clinical outcomes.
Dosage and Administration:
The dosage of CA ATRA (Tretinoin) varies depending on factors such as the patient’s age, weight, and overall health condition, as well as the specific treatment protocol prescribed by the healthcare provider. It is typically administered orally in capsule form, usually once daily. The capsules should be swallowed whole with a glass of water, preferably with food to reduce gastrointestinal side effects. It is important to follow the dosage instructions provided by the healthcare provider and to complete the full course of treatment as prescribed.
Side Effects:
Common side effects associated with CA ATRA (Tretinoin) may include headache, nausea, vomiting, diarrhea, abdominal pain, skin rash, and bone pain. These side effects are usually mild to moderate in severity and may subside with continued use. However, some patients may experience more serious side effects such as leukocytosis (high white blood cell count), hypotension, or respiratory distress. It is important to report any persistent or bothersome side effects to the healthcare provider promptly.
Precautions:
Before starting treatment with CA ATRA (Tretinoin), patients should inform their healthcare provider about any underlying medical conditions, allergies, or medications they are currently taking. CA ATRA may interact with certain medications, so it is essential to discuss potential drug interactions with the healthcare provider. Pregnant or breastfeeding women should avoid using CA ATRA due to potential risks to the fetus or infant. Regular monitoring of blood counts and liver function tests may be necessary during treatment with CA ATRA to monitor for potential adverse effects.
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