Description
Description: Campto is an injectable medication containing Irinotecan, a topoisomerase I inhibitor used in the treatment of various types of cancer. It is primarily indicated for colorectal cancer and other solid tumors.
Mechanism of Action: Irinotecan exerts its anticancer effects by inhibiting the activity of topoisomerase I enzyme, which is essential for DNA replication and repair. By interfering with this process, Irinotecan induces DNA damage, leading to cell death in rapidly dividing cancer cells.
Indications: Campto is indicated for the treatment of patients with metastatic colorectal cancer who have failed prior therapy with fluorouracil-based regimens. It may also be used in combination with other chemotherapy agents for the treatment of other solid tumors, including lung cancer and pancreatic cancer.
Dosage and Administration: Campto is administered intravenously over a specific infusion period as determined by the healthcare provider. The dosage and schedule may vary depending on the patient’s condition, treatment regimen, and response to therapy. It is crucial to follow the dosing instructions provided by the prescribing healthcare professional.
Precautions and Warnings:
- Campto should be administered under the supervision of a qualified healthcare professional experienced in the use of chemotherapy agents.
- Patients should be monitored closely for signs of myelosuppression, diarrhea, and other adverse reactions during treatment with Campto.
- Patients with severe diarrhea may require treatment with antidiarrheal medications and dose modifications.
- Campto may cause severe infusion reactions, including anaphylaxis. Patients should be closely monitored during infusion, and appropriate medical interventions should be available.
- Prior to initiating treatment with Campto, patients should undergo a comprehensive medical evaluation, including assessment of liver function, renal function, and hematologic parameters.
- Campto may cause fetal harm if administered to pregnant women. Women of childbearing potential should use effective contraception during treatment and for a certain period thereafter.
Adverse Reactions: Common adverse reactions associated with Campto include diarrhea, nausea, vomiting, fatigue, neutropenia, anemia, alopecia, abdominal pain, and fever. Serious adverse reactions may include severe neutropenia, febrile neutropenia, and interstitial lung disease.
Storage: Campto should be stored at controlled room temperature away from moisture and heat. It should be kept out of reach of children and disposed of properly in accordance with local regulations.
Disclaimer: The information provided here is for informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. Always consult your healthcare provider regarding any questions or concerns you may have about your condition or treatment options.
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