Description
Chemical name: 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
Formula: C28H38N6O11S
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
CENFORCE-100
Description:
Cenforce-100 (Generic Viagra, Sildenafil Citrate) is a medication containing Sildenafil Citrate as its active substance, manufactured by Centurion Laboratories. Each tablet contains 100 milligrams of Sildenafil Citrate, a phosphodiesterase type 5 (PDE5) inhibitor. CENFORCE-100 is primarily used to treat erectile dysfunction (ED) in men, helping them achieve and maintain an erection sufficient for satisfactory sexual activity.
Key Points:
- Active Substance:
- Sildenafil Citrate: Sildenafil Citrate is a potent and selective inhibitor of phosphodiesterase type 5 (PDE5), an enzyme responsible for the degradation of cyclic guanosine monophosphate (cGMP). By inhibiting PDE5, Sildenafil increases the levels of cGMP in the corpus cavernosum during sexual stimulation, leading to smooth muscle relaxation and enhanced blood flow to the penis, thereby facilitating an erection.
- Indications:
- CENFORCE-100 is indicated for the treatment of erectile dysfunction (ED), a condition characterized by the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. It is also sometimes used off-label to treat pulmonary arterial hypertension (PAH) due to its vasodilatory effects.
- Mechanism of Action:
- Sildenafil Citrate works by blocking the enzyme PDE5, which results in increased levels of cGMP. This chemical relaxes smooth muscle cells and increases blood flow to the penis, leading to an erection in the presence of sexual stimulation. It does not produce an erection without sexual arousal.
- Dosage and Administration:
- The recommended starting dose of CENFORCE-100 is 50 milligrams, taken as needed about one hour before sexual activity. Depending on efficacy and tolerability, the dose may be increased to 100 milligrams or decreased to 25 milligrams. It should not be taken more than once daily. For best results, take the tablet with water on an empty stomach or after a light meal.
- Precautions:
- CENFORCE-100 should be used with caution in patients with cardiovascular disease, renal or hepatic impairment, and those taking medications that can interact with Sildenafil, such as nitrates or alpha-blockers. It is contraindicated in patients with severe cardiovascular conditions or those who have been advised against sexual activity.
- Possible Side Effects:
- Common side effects of Sildenafil Citrate include headache, flushing, dyspepsia (indigestion), nasal congestion, dizziness, and visual disturbances. Rare but serious side effects may include priapism (prolonged erection), sudden hearing loss, and myocardial infarction (heart attack). Immediate medical attention is necessary for serious adverse effects.
Note: CENFORCE-100 is an effective treatment option for erectile dysfunction, helping men achieve and maintain erections for satisfactory sexual activity. It is important to use this medication under the guidance of a healthcare professional, adhering to prescribed dosages and being aware of potential side effects and interactions with other medications. Regular follow-up with a healthcare provider is recommended to ensure safe and effective use.
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