Description
Derise is a medication manufactured by Hetero Healthcare Ltd. containing the active ingredient Darbepoetin Alfa. It is formulated as an injectable solution and is primarily used in the treatment of anemia associated with chronic kidney disease (CKD), chemotherapy-induced anemia, and anemia in patients with certain types of cancer. Darbepoetin Alfa is a synthetic form of erythropoietin, a hormone produced by the kidneys that stimulates the production of red blood cells in the bone marrow.
Key Features:
- Anemia Management: Derise is indicated for the management of anemia in patients with chronic kidney disease who are undergoing dialysis or are not on dialysis. It helps to increase red blood cell production and raise hemoglobin levels, improving symptoms such as fatigue, weakness, and shortness of breath.
- Chemotherapy-Induced Anemia: Derise is used to treat anemia in patients receiving chemotherapy for cancer. Chemotherapy can suppress bone marrow function, leading to decreased red blood cell production and anemia. Darbepoetin Alfa stimulates the bone marrow to produce more red blood cells, reducing the need for blood transfusions and improving quality of life.
- Cancer-Related Anemia: Patients with certain types of cancer, such as non-myeloid malignancies, may develop anemia as a result of the disease or its treatment. Derise can help manage anemia in these patients by stimulating red blood cell production and alleviating symptoms associated with low hemoglobin levels.
- Long-Lasting Effects: Darbepoetin Alfa has a longer half-life compared to conventional erythropoietin therapy, allowing for less frequent dosing and improved patient convenience. This reduces the burden of treatment and enhances compliance among patients with chronic anemia.
Usage:
- Derise is administered as a subcutaneous injection or intravenous infusion under the supervision of a healthcare professional.
- The dosage and frequency of administration depend on the patient’s condition, response to treatment, and hemoglobin levels.
- Treatment with Derise should be initiated and monitored by a healthcare provider experienced in the management of anemia associated with chronic kidney disease or cancer.
Safety Precautions:
- Use Derise with caution in patients with uncontrolled hypertension, thrombotic events, or pure red cell aplasia (PRCA).
- Monitor hemoglobin levels regularly during treatment with Derise and adjust the dosage as needed to maintain target hemoglobin levels.
- Do not exceed the recommended dosage of Derise, as higher doses may increase the risk of cardiovascular events and mortality.
- Inform your healthcare provider about any medications you are taking, including prescription drugs, over-the-counter medicines, vitamins, and supplements, as they may interact with Darbepoetin Alfa.
Derise, manufactured by Hetero Healthcare Ltd., is an effective treatment option for managing anemia associated with chronic kidney disease, chemotherapy, and certain types of cancer. Trust Derise to help improve hemoglobin levels and enhance quality of life for patients with anemia.
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