Description
Description: GLUCOPHAGE 1000 mg tablets are an oral medication manufactured by Merck. Each tablet contains 1000 milligrams (mg) of the active substance Metformin Hydrochloride. Metformin is a widely used medication for the management of type 2 diabetes mellitus, helping to control blood sugar levels in individuals with this condition.
Active Substance: The active substance in GLUCOPHAGE 1000 mg tablets is Metformin Hydrochloride. Metformin belongs to the class of biguanide medications and works by reducing the amount of glucose produced by the liver and improving the sensitivity of muscle cells to insulin. This helps to lower blood sugar levels and improve glycemic control in individuals with type 2 diabetes.
Manufacturer: GLUCOPHAGE 1000 mg tablets are manufactured by Merck, a global pharmaceutical company known for its commitment to innovation and quality in healthcare. Merck is dedicated to developing medications that address unmet medical needs and improve patient outcomes.
Uses: GLUCOPHAGE 1000 mg tablets are indicated for the management of type 2 diabetes mellitus, particularly in individuals who cannot achieve adequate glycemic control through diet and exercise alone. It may be used alone or in combination with other antidiabetic medications, such as insulin or sulfonylureas.
How to Use: GLUCOPHAGE 1000 mg tablets should be taken orally with meals to reduce gastrointestinal side effects, unless otherwise directed by a healthcare professional. The dosage and frequency of administration will vary depending on factors such as the patient’s blood sugar levels, kidney function, and response to treatment. It is essential to follow the dosage instructions provided by the healthcare provider.
Storage Conditions: GLUCOPHAGE 1000 mg tablets should be stored according to the manufacturer’s instructions, typically at room temperature away from heat, light, and moisture. The tablets should be kept in their original packaging and out of reach of children and pets.
Precautions:
- GLUCOPHAGE 1000 mg tablets should be used with caution in patients with certain medical conditions, such as kidney impairment, liver disease, or heart failure.
- It is essential to monitor kidney function regularly during treatment with GLUCOPHAGE, as the medication may increase the risk of lactic acidosis, a potentially life-threatening condition.
- GLUCOPHAGE should not be used in patients with severe renal impairment (eGFR less than 30 mL/min/1.73 m²) or metabolic acidosis.
Contraindications: GLUCOPHAGE 1000 mg tablets are contraindicated in patients with a known hypersensitivity to Metformin Hydrochloride or any of the components in the formulation. It should not be used in patients with severe renal impairment, metabolic acidosis, or diabetic ketoacidosis.
Side Effects: Common side effects associated with GLUCOPHAGE 1000 mg tablets may include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and abdominal discomfort. These side effects are usually mild and transient and can often be minimized by taking the medication with meals. More severe side effects, such as lactic acidosis, are rare but can be serious. Promptly report any unusual or severe symptoms to a healthcare provider.
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