Description
Chemical name: 1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
Formula: C28H38N6O11S
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
MALEGRA-50
Malegra-50, one of the generics of Viagra,is a medication designed for the treatment of erectile dysfunction (ED) in men, containing 50 mg of the active substance Sildenafil Citrate per tablet. Manufactured by Sunrise Remedies, MALEGRA-50 is part of a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. Sildenafil Citrate works by increasing blood flow to the penis, helping to achieve and maintain an erection suitable for sexual activity.
Active Substance:
- Sildenafil Citrate: Sildenafil Citrate is a potent PDE5 inhibitor that enhances erectile function by relaxing the blood vessels in the penis, allowing increased blood flow during sexual arousal.
Manufacturer:
- Sunrise Remedies: Sunrise Remedies is a reputable pharmaceutical company known for producing high-quality medications, including those for treating erectile dysfunction. The company adheres to stringent manufacturing standards to ensure the safety, efficacy, and reliability of its products.
Uses: MALEGRA-50 (Sildenafil Citrate Tablets 50 mg) is primarily prescribed for:
- Erectile Dysfunction: It is used to treat erectile dysfunction, a condition where a man is unable to achieve or maintain an erection sufficient for satisfactory sexual performance.
How to Use: MALEGRA-50 should be taken orally, approximately one hour before sexual activity. The tablet should be swallowed whole with a glass of water. The effects of Sildenafil can last for up to four to six hours. It is important not to take more than one tablet within a 24-hour period.
Storage Conditions: MALEGRA-50 tablets should be stored in a cool, dry place, away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Proper storage conditions help maintain the integrity and effectiveness of the tablets.
Mechanism of Action: Sildenafil Citrate works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which results in the relaxation of smooth muscle in the corpus cavernosum and allows increased blood flow to the penis. This mechanism facilitates the achievement and maintenance of an erection in response to sexual stimulation.
Precautions:
- MALEGRA-50 should be used with caution in individuals with cardiovascular conditions, such as heart disease, hypertension, or a history of stroke. It may also interact with medications containing nitrates, leading to a dangerous drop in blood pressure.
- Patients should inform their healthcare provider of any underlying medical conditions, especially those affecting the heart, liver, or kidneys.
- Avoid consuming large amounts of alcohol or grapefruit products while taking this medication, as they can interfere with its effectiveness.
Contraindications: MALEGRA-50 is contraindicated in individuals with known hypersensitivity to Sildenafil or any other component of the formulation. It should not be used by individuals taking nitrate medications or those with severe cardiovascular disorders that make sexual activity inadvisable.
Drug Interactions: Sildenafil Citrate may interact with various medications, including nitrates (used for chest pain), alpha-blockers (used for hypertension), and other PDE5 inhibitors. It is essential to inform the healthcare provider of all medications currently being taken to avoid potential interactions.
Side Effects: Common side effects of MALEGRA-50 may include headache, flushing, dyspepsia (indigestion), nasal congestion, dizziness, and visual disturbances. Most side effects are mild and temporary. However, if an erection lasts more than four hours (priapism) or if severe side effects occur, such as chest pain, severe dizziness, or sudden loss of vision or hearing, immediate medical attention should be sought.
Patients are advised to consult their healthcare provider for personalized advice and information regarding MALEGRA-50 (Sildenafil Citrate Tablets 50 mg), including its proper use, dosage, and potential side effects.
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