Description
Mavenclad (cladribine) is a prescription medication used to treat relapsing-remitting multiple sclerosis (RRMS). It is an oral medication that is taken by mouth and is manufactured by EMD Serono.
Uses:
Mavenclad is primarily used to treat RRMS, a chronic inflammatory disease of the central nervous system that disrupts the normal communication between the brain and other parts of the body. The medication works by targeting and killing B and T lymphocytes, immune cells that contribute to the inflammation and damage of the central nervous system in patients with RRMS. By reducing the number of these cells, Mavenclad reduces the frequency and severity of MS relapses and slows down the progression of the disease.
Storage Conditions:
Mavenclad should be stored at room temperature between 68-77°F (20-25°C). The medication should be kept in its original packaging and stored in a dry place, away from heat and light. Any unused or expired medication should be disposed of properly according to local regulations.
Mechanism of Action:
Mavenclad works by targeting and killing B and T lymphocytes, immune cells that contribute to the inflammation and damage of the central nervous system in patients with RRMS. By reducing the number of these cells, the medication reduces the frequency and severity of MS relapses and slows down the progression of the disease.
HOW TO USE:
Mavenclad is taken orally in two treatment courses over two years. The first course is administered over two years, with the first course of treatment occurring in the first year and the second course in the second year. Each treatment course consists of two treatment weeks, one year apart. During each treatment week, individuals take a total of four tablets, one tablet each day for four or five consecutive days, depending on their body weight. It is essential to follow the prescribed schedule and not to receive more or less medication than recommended.
Precautions:
Individuals receiving Mavenclad should inform their medical provider of any medical conditions they have, such as recent or ongoing infections or immunodeficiency disorders, as well as any allergies. The medication may increase the risk of cancer or infections, and individuals should avoid contact with individuals who have infectious diseases. It is also important to use contraception during treatment and for six months after treatment with Mavenclad, as it may harm a developing fetus.
Drug Interactions:
Mavenclad may interact with other medications, such as antiviral drugs or immunosuppressive agents, and individuals should inform their medical provider of all medications, including over-the-counter drugs and supplements, that they are taking before starting treatment with Mavenclad.
Contraindications:
Mavenclad is contraindicated in individuals who have a hypersensitivity to the medication or any of its components. The safety and effectiveness of the medication have not been established in children under the age of 18 or pregnant and breastfeeding women.
Overdose:
In the event of an overdose, individuals should seek immediate medical attention. Symptoms of an overdose may include nausea, vomiting, fever, chills, or infection.
Adverse Reactions:
Mavenclad may cause several side effects, including upper respiratory tract infections, headaches, low white blood cell counts, and skin rashes. More severe side effects may include liver damage, bone marrow suppression, and an increased risk of cancer or infections. Individuals who experience any of these side effects should inform their medical provider immediately.
In conclusion, Mavenclad is a prescription medication used to treat RRMS by reducing the frequency and severity of MS relapses and slowing down the progression of the disease by targeting and killing B and T lymphocytes. Mavenclad is stored at room temperature and taken orally in two treatment courses over two years, with essential precautions to be taken while using the medication. Mavenclad may cause side effects, and medical attention should be sought immediately in case of overdose. Mavenclad should not be used by individuals with hypersensitivity to any of its components and requires caution when used by pregnant or breastfeeding women.
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