Description
Description:
Nebido is a medication manufactured by Bayer, containing the active substance Testosterone Undecanoate. Each vial of Nebido typically contains 1000 mg of Testosterone Undecanoate in a 4 mL solution.
Active Substance:
Testosterone Undecanoate: Testosterone Undecanoate is a long-acting ester of testosterone, an androgen and anabolic steroid hormone. It is used in hormone replacement therapy (HRT) for the treatment of conditions associated with deficient or absent endogenous testosterone production, such as hypogonadism. Testosterone Undecanoate is gradually released into the bloodstream after intramuscular injection, providing sustained testosterone levels over an extended period.
Manufacturer:
Bayer: Nebido is manufactured by Bayer, a multinational pharmaceutical company known for its commitment to innovation and quality in healthcare products. Bayer adheres to strict quality control measures and regulatory standards to ensure the safety, efficacy, and reliability of its medications.
Indications:
Nebido, containing Testosterone Undecanoate, is indicated for:
- Hormone replacement therapy (HRT) in adult males with hypogonadism or testosterone deficiency
- Improvement of symptoms associated with deficient or absent endogenous testosterone production, such as low libido, erectile dysfunction, fatigue, decreased muscle mass, and mood disturbances
Nebido provides a long-acting testosterone replacement option, requiring less frequent dosing compared to shorter-acting testosterone preparations.
Dosage and Administration:
The recommended dosage of Nebido (Testosterone Undecanoate) may vary depending on individual patient characteristics, such as age, weight, and severity of testosterone deficiency. It is typically administered by intramuscular injection into the gluteal muscle at intervals of 10 to 14 weeks. The initial loading dose may be higher, followed by maintenance doses to maintain therapeutic testosterone levels.
Side Effects:
Common side effects associated with Nebido (Testosterone Undecanoate) may include:
- Injection site reactions, such as pain, redness, or swelling
- Acne
- Increased hematocrit or hemoglobin levels
- Fluid retention
- Increased prostate-specific antigen (PSA) levels
- Mood changes or irritability
More serious side effects, although rare, may include cardiovascular events, liver toxicity, or exacerbation of sleep apnea. Patients should be monitored regularly for signs of adverse effects, and any unusual or severe symptoms should be reported to the healthcare provider promptly.
Precautions:
Before starting treatment with Nebido (Testosterone Undecanoate), patients should undergo a thorough medical evaluation to assess testosterone deficiency and rule out underlying conditions that may contraindicate testosterone replacement therapy. Nebido should not be used in patients with prostate or breast cancer, severe hepatic impairment, or hypersensitivity to testosterone or any of its ingredients. Pregnant or breastfeeding women and children should avoid contact with Nebido to prevent potential virilization or adverse effects. Nebido should be used with caution in patients with cardiovascular risk factors, such as hypertension, hyperlipidemia, or a history of thromboembolic events. Regular monitoring of testosterone levels, hematocrit, PSA, and other relevant parameters may be necessary during treatment with Nebido to optimize therapy and minimize the risk of adverse effects. Nebido should be administered by a qualified healthcare professional experienced in the management of testosterone replacement therapy.
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