Buy Onivyde (irinotecan hydrochloride trihydrate) Online For Sale

$990.15

DISEASE INDICATIONS: Pancreatic Cancer

MANUFACTURER: Baxalta Innovations GmbH

USAGE: Intravenous

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Health Canada

Therapeutic Goods Administration (TGA)

Medsafe (NZ)

Onivyde (irinotecan hydrochloride trihydrate) is an injectable medication used to treat metastatic adenocarcinoma of the pancreas. It works by inhibiting topoisomerase I, an enzyme necessary for DNA replication in cancer cells.

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Description

Onivyde (irinotecan hydrochloride trihydrate) is an injectable medication used to treat metastatic adenocarcinoma of the pancreas. The drug belongs to a class of medications known as topoisomerase inhibitors, which work by blocking a specific enzyme involved in the replication of DNA in cancer cells.

Uses:

Onivyde is used in combination with fluorouracil (a chemotherapy drug) and leucovorin (a medication that increases the effectiveness of chemotherapy drugs) to treat patients with metastatic adenocarcinoma of the pancreas who have been previously treated with gemcitabine (another chemotherapy drug).

Storage Conditions:

Onivyde should be stored in the refrigerator at a temperature ranging from 2-8°C (36-46°F). The medication should be protected from light.

Mechanism of Action:

Onivyde works by inhibiting topoisomerase I, an enzyme that is necessary for DNA replication in cancer cells. By blocking this enzyme, Onivyde prevents the cancer cells from dividing and spreading.

HOW TO USE:

Onivyde is an injection that is administered intravenously by a healthcare professional in a medical setting. The medication is typically given once every two weeks, along with fluorouracil and leucovorin.

Precautions:

Onivyde has been associated with severe side effects, including neutropenia (low white blood cell count), diarrhea, fatigue, nausea, vomiting, and dehydration. In some cases, these side effects can be life-threatening. Patients who have had severe reactions to other medications should use Onivyde with caution.

Drug Interactions:

Onivyde may interact with other medications, particularly those that affect liver function. Patients taking any medications that may affect liver function should inform their healthcare provider before taking Onivyde.

Contraindications:

Onivyde is contraindicated in patients with a history of severe hypersensitivity to irinotecan or any of the components of the medication. It is also not recommended for use in patients with severe allergic reactions to other medications or in patients with severe liver function impairment.

Overdose:

There is currently no established protocol for Onivyde overdose. Medical attention should be sought immediately if an overdose is suspected.

Adverse Reactions:

Common side effects of Onivyde include diarrhea, fatigue, nausea, vomiting, decreased appetite, hair loss, and abdominal pain. Additionally, it may cause anemia, neutropenia, and dehydration. Patients should inform their medical provider of any abnormal and persistent symptoms during treatment.

In conclusion, Onivyde (irinotecan hydrochloride trihydrate) is an injectable medication used in combination with other drugs to treat metastatic adenocarcinoma of the pancreas. It works by inhibiting topoisomerase I, which prevents the replication of cancer cells. The medication must be administered by a healthcare professional in a medical setting. Patients should use caution if they have had severe reactions to other medications. Common side effects include fatigue, nausea, vomiting, and diarrhea.

Additional information

Package

1 vial of 50 mg/10 mL

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