Description
Description:
ORTHOVISC is a viscosupplement injection used for the relief of knee pain associated with osteoarthritis. It contains hyaluronic acid, a naturally occurring substance found in the synovial fluid of joints, which helps lubricate and cushion the joint surfaces. Here’s a detailed description:
Indications: ORTHOVISC is indicated for the treatment of knee pain due to osteoarthritis in patients who have failed to respond adequately to conservative non-pharmacologic therapy and simple analgesics.
Active Substance:
- Hyaluronic Acid: Hyaluronic acid is a glycosaminoglycan that is naturally present in the synovial fluid of joints. It serves as a lubricant and shock absorber, helping to reduce friction and cushion the joint surfaces during movement. In osteoarthritis, the natural hyaluronic acid in the joint may become depleted, leading to increased joint pain and stiffness. ORTHOVISC supplements the natural hyaluronic acid in the knee joint, providing lubrication and cushioning to alleviate pain and improve joint function.
Dosage Form: ORTHOVISC is supplied in the form of a pre-filled syringe containing 2 mL of solution, with each syringe containing 15 mg of hyaluronic acid.
Administration: ORTHOVISC is administered by intra-articular injection into the knee joint. The injection is typically performed by a healthcare professional in a clinical setting. The recommended dosing regimen may vary, but it commonly involves a series of injections spaced over several weeks to achieve optimal therapeutic benefits.
Mechanism of Action: ORTHOVISC works by replenishing the natural hyaluronic acid in the synovial fluid of the knee joint. Hyaluronic acid helps lubricate and cushion the joint surfaces, reducing friction and improving joint mobility. By restoring the viscoelastic properties of the synovial fluid, ORTHOVISC alleviates pain, reduces inflammation, and improves joint function in patients with osteoarthritis.
Benefits:
- Pain Relief: ORTHOVISC provides effective relief from knee pain associated with osteoarthritis, helping patients to manage their symptoms and improve their quality of life.
- Improved Joint Function: By lubricating and cushioning the joint surfaces, ORTHOVISC improves joint mobility and function, allowing patients to engage in daily activities with greater ease.
- Long-lasting Relief: The effects of ORTHOVISC may last for several months, providing sustained pain relief and functional improvement in patients with osteoarthritis.
Side Effects: Common side effects associated with ORTHOVISC may include:
- Transient pain or swelling at the injection site
- Mild to moderate local reactions, such as redness or warmth
- Temporary exacerbation of knee pain or stiffness
- Rarely, allergic reactions or infection at the injection site
Contraindications and Precautions: ORTHOVISC is contraindicated in patients with known hypersensitivity to hyaluronic acid or any of the components of the formulation. It should be used with caution in patients with a history of allergic reactions to other hyaluronic acid products or in patients with knee joint infections or skin diseases around the injection site.
Storage: ORTHOVISC should be stored according to the manufacturer’s instructions, typically at room temperature away from light and moisture. The product should be inspected visually before use, and any syringes with visible signs of damage or contamination should not be used.
As with any medical treatment, the use of ORTHOVISC should be supervised by a qualified healthcare professional. Patients should receive education on the expected benefits and potential side effects of the treatment, and they should be monitored closely for any adverse reactions during and after the injection procedure. Close communication between patients, caregivers, and healthcare providers is essential for optimizing treatment outcomes and ensuring patient safety.
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