Buy Symkevi (tezacaftor/ivacaftor) Online For Sale

$5,615.40

DISEASE INDICATIONS: Cystic Fibrosis

MANUFACTURER: Vertex Pharmaceuticals (Europe) Ltd

USAGE: Oral

MEDICINE APPROVED BY:

European Medical Agency (EMA)

Food and Drug Administration (FDA)

Symkevi (tezacaftor/ivacaftor) is a combination medication used to treat cystic fibrosis in patients aged 12 years and older who have certain genetic mutations.

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Description

Symkevi is a prescription medication that combines two active ingredients: tezacaftor and ivacaftor. It is primarily used in the treatment of cystic fibrosis (CF), a genetic disorder that affects the lungs and other organs, leading to the production of thick and sticky mucus. Symkevi is specifically indicated for individuals with CF who have certain mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Here is a comprehensive description of Symkevi:

1. Mechanism of Action:

  • Symkevi is a CFTR modulator, which means it helps improve the function of the defective CFTR protein in people with specific CF mutations. Tezacaftor in Symkevi assists in the processing and trafficking of the CFTR protein, while ivacaftor enhances the function of the protein itself.
  • Together, these actions help improve the flow of salt and fluids in and out of cells, reducing the thickness of mucus in the airways and improving lung function.

2. Indications:

  • Symkevi is indicated for the treatment of cystic fibrosis in individuals aged six years and older who have specific CF mutations. The specific mutations for which Symkevi is approved may vary by region.

3. Dosage and Administration:

  • Symkevi is available in tablet form for oral administration.
  • The dosage and frequency of Symkevi will be determined by a healthcare provider based on the patient’s age, weight, and specific CF mutations.
  • Patients should follow the prescribed dosing instructions carefully.

4. Clinical Efficacy:

  • Clinical trials have demonstrated that Symkevi can improve lung function and respiratory symptoms in individuals with CF who have specific CF mutations responsive to the medication.
  • It can also lead to better nutritional status and overall quality of life for patients.

5. Side Effects:

  • Common side effects of Symkevi may include respiratory tract infections, nausea, headache, diarrhea, and abdominal pain.
  • Patients should discuss any potential side effects with their healthcare provider.

6. Monitoring and Precautions:

  • Patients receiving Symkevi may require regular monitoring of lung function, nutritional status, and overall health.
  • It is important to inform healthcare providers of all other medications and medical conditions, as potential drug interactions may occur.

Symkevi represents an important advancement in the treatment of cystic fibrosis for individuals with specific CF gene mutations. By addressing the underlying genetic defect, Symkevi can help improve lung function and quality of life for these patients. It should be used under the guidance and supervision of qualified healthcare professionals who can assess its appropriateness for individual cases.

Additional information

Package

28 tablets of 100 mg/150 mg

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