Description
Description: Tilidin 150/12mg is a potent analgesic medication manufactured by Sandoz. Each pack contains 20 tablets, with each tablet comprising 150 milligrams (mg) of Tilidin and 12 milligrams (mg) of Naloxone. This combination is formulated to provide effective pain relief while minimizing the potential for misuse and dependence.
Active Substances:
- Tilidin: An opioid analgesic that acts on the central nervous system to relieve moderate to severe pain. Tilidin is converted in the body to its active form, nortilidine, which binds to opioid receptors, altering the perception of and response to pain.
- Naloxone: An opioid antagonist included in the formulation to counteract the potential for opioid misuse and abuse. Naloxone works by blocking the effects of opioids at the receptor level, which helps to prevent the euphoria associated with opioid use if the medication is tampered with (e.g., crushed and injected).
Manufacturer: Tilidin 150/12mg is manufactured by Sandoz, a global leader in generic pharmaceuticals and biosimilars. Sandoz is committed to providing high-quality, affordable medications that meet rigorous safety and efficacy standards.
Formulation: Each Tilidin 150/12mg tablet contains:
- 150 mg of Tilidin
- 12 mg of Naloxone
Uses: Tilidin 150/12mg tablets are indicated for the management of moderate to severe pain that requires opioid analgesia and for which alternative treatments are inadequate.
How to Use: Tilidin 150/12mg tablets should be taken orally, as prescribed by a healthcare professional. The dosage and frequency will depend on the severity of the pain and the patient’s response to treatment. It is important to follow the prescribed dosage and not to exceed the recommended amount to avoid the risk of side effects and dependency.
Storage Conditions: Tilidin 150/12mg should be stored at room temperature, away from moisture, heat, and direct light. Keep the medication in its original packaging and out of reach of children and pets.
Precautions:
- Tilidin 150/12mg should be used with caution in patients with a history of substance abuse, respiratory issues, or liver and kidney impairment.
- Patients should avoid consuming alcohol and other central nervous system depressants while taking this medication.
- It is essential to monitor for signs of misuse, abuse, and addiction.
Contraindications:
- Tilidin 150/12mg is contraindicated in individuals with hypersensitivity to Tilidin, Naloxone, or any of the components of the formulation.
- It should not be used in patients with severe respiratory depression, acute or severe bronchial asthma, or gastrointestinal obstruction.
Side Effects: Common side effects of Tilidin 150/12mg may include nausea, vomiting, dizziness, drowsiness, constipation, and sweating. Serious side effects can include respiratory depression, severe hypotension, and allergic reactions. If any severe or unusual symptoms occur, seek medical attention immediately.
Interactions:
- Tilidin may interact with other central nervous system depressants, such as benzodiazepines, sedatives, and alcohol, increasing the risk of respiratory depression and sedation.
- It may also interact with other medications that affect the cytochrome P450 enzyme system, altering the effectiveness and safety of the medication.
- Concomitant use of MAO inhibitors and opioids can cause serotonin syndrome, a potentially life-threatening condition.
Overdose: In case of an overdose, immediate medical attention is required. Symptoms of an overdose may include severe drowsiness, slow or difficult breathing, and loss of consciousness. Naloxone, included in the formulation, can help mitigate some of the opioid effects in an overdose situation. However, additional medical interventions may be necessary.
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