Description
Chemical name: (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
Formula: C15H12I3NO4
Description: TIROMEL 25mcg, manufactured by Abdi Ibrahim, is a medication that contains Liothyronine Sodium as its active ingredient. Liothyronine is a synthetic form of the thyroid hormone triiodothyronine (T3), used primarily for the treatment of hypothyroidism, a condition where the thyroid gland does not produce sufficient hormones. TIROMEL helps restore normal thyroid hormone levels, thereby regulating metabolism, energy levels, and overall well-being.
Active Substance:
- Liothyronine Sodium: A synthetic thyroid hormone (T3) that mimics the natural hormone produced by the thyroid gland, playing a crucial role in regulating various metabolic processes in the body.
Indications: TIROMEL 25mcg is indicated for:
- Hypothyroidism: To replace missing thyroid hormone in patients with an underactive thyroid gland, alleviating symptoms such as fatigue, weight gain, and depression.
- Myxedema: Severe hypothyroidism characterized by swelling of the skin and tissues.
- Goiter: To reduce thyroid gland enlargement.
- Thyroid Cancer: As part of thyroid suppression therapy.
- Diagnostic Use: In thyroid suppression tests.
Mechanism of Action:
- Metabolic Regulation: Liothyronine Sodium works by increasing the basal metabolic rate, influencing the synthesis and utilization of proteins, fats, and carbohydrates, and regulating the growth and development of tissues.
- Mimicking Natural Hormones: As a synthetic form of T3, it mimics the action of the natural thyroid hormone, thereby normalizing metabolic processes in hypothyroid patients.
Benefits:
- Rapid Onset of Action: TIROMEL has a quicker onset of action compared to other thyroid hormone replacements, providing faster relief from hypothyroid symptoms.
- Effective Metabolic Regulation: Helps maintain normal metabolic rates, energy levels, and overall physical and mental health in patients with thyroid hormone deficiency.
- Versatility in Use: Can be used for multiple thyroid-related conditions, from hypothyroidism to thyroid cancer management.
Dosage and Administration:
- Recommended Dosage: The typical starting dose is 25 mcg daily, with possible gradual increments of 12.5 to 25 mcg every 1 to 2 weeks, based on patient response and thyroid hormone levels.
- Administration: The pill should be taken orally, preferably in the morning on an empty stomach, at least 30 minutes before breakfast. Consistency in the timing of doses is important for maintaining stable hormone levels.
Storage: TIROMEL should be stored at room temperature, between 15°C to 30°C (59°F to 86°F), away from moisture, heat, and direct sunlight. Keep the medication out of reach of children and pets, and ensure the blister pack remains intact until use to preserve the efficacy and safety of the tablets.
Side Effects: Common side effects may include:
- Palpitations: A feeling of irregular or forceful heartbeats.
- Increased Appetite: Due to the increased metabolic rate.
- Nervousness: Anxiety or restlessness.
- Weight Loss: Resulting from increased metabolism.
- Sweating and Heat Intolerance: Due to enhanced thermogenesis.
Precautions:
- Cardiovascular Health: Use with caution in patients with cardiovascular disorders such as hypertension, arrhythmias, or ischemic heart disease, as thyroid hormones can increase cardiac workload.
- Diabetes: Patients with diabetes should monitor blood glucose levels closely, as thyroid hormone therapy can affect glucose metabolism.
- Adrenal Insufficiency: Ensure that adrenal insufficiency is treated before starting TIROMEL therapy, as thyroid hormones can exacerbate adrenal issues.
Contraindications:
- Uncontrolled Thyrotoxicosis: TIROMEL is contraindicated in patients with uncontrolled overactive thyroid.
- Acute Myocardial Infarction: Should not be used during acute phases of heart attack.
- Hypersensitivity: Contraindicated in individuals with known hypersensitivity to liothyronine or any other components of the formulation.
In summary, TIROMEL 25mcg by Abdi Ibrahim is a potent thyroid hormone replacement therapy that effectively manages conditions associated with thyroid hormone deficiency. By restoring normal thyroid hormone levels, it helps regulate metabolism, energy levels, and overall health, providing significant relief for patients with hypothyroidism and other related conditions.
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