Description
Chemical name: 1-(((3-(3,4-dihydro-5-methyl)-4-oxo-7-propylimidazo(5,1-f)-as-triazin-2-yl)-4-ethoxyphenyl)sulfonyl)-4-ethylpiperazine
Formula: C23H32N6O4S
Anabolic activity index: not a steroid
Androgenic activity index: not a steroid
VALIF-20
Valif-20 (Generic Levitra, Vardenafil) is a medication manufactured by Ajanta Pharma, containing vardenafil as the active substance. Each box contains 10 tablets, with each tablet providing 20 milligrams of vardenafil. VALIF-20 is used to treat erectile dysfunction (ED) in men, helping them achieve and maintain an erection when sexually stimulated.
Active Substance: Vardenafil is a phosphodiesterase type 5 (PDE5) inhibitor. It works by increasing blood flow to the penis during sexual stimulation, enabling a man to achieve and sustain an erection.
Indications: VALIF-20 is indicated for the treatment of erectile dysfunction (ED), which is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. It is effective in men with ED regardless of the underlying cause.
Mechanism of Action:
- Vardenafil inhibits the PDE5 enzyme, responsible for the degradation of cyclic guanosine monophosphate (cGMP).
- By inhibiting PDE5, vardenafil increases levels of cGMP, leading to relaxation of smooth muscle and increased blood flow to the corpus cavernosum, resulting in an erection.
- The effectiveness of vardenafil depends on sexual stimulation, which triggers the initial release of nitric oxide (NO) and subsequent increase in cGMP levels.
Administration:
- VALIF-20 is administered orally, typically with water.
- The recommended starting dose is one 20 mg tablet taken approximately 25 to 60 minutes before sexual activity.
- VALIF-20 can be taken with or without food; however, a high-fat meal may delay its onset of action.
- The maximum recommended dosing frequency is once per day.
Monitoring:
- Patients using VALIF-20 should be monitored for efficacy and any adverse effects.
- It is important to have follow-up consultations with a healthcare provider to adjust the dose if necessary and to discuss any concerns or side effects.
Side Effects: Common side effects associated with the use of VALIF-20 may include:
- Headache
- Flushing
- Dyspepsia (indigestion)
- Nasal congestion
- Dizziness
- Visual disturbances (e.g., changes in color vision, blurred vision)
Serious but rare side effects may include:
- Priapism (prolonged and painful erection)
- Sudden hearing loss
- Sudden vision loss in one or both eyes
Precautions:
- VALIF-20 should not be used by individuals taking nitrates for chest pain, as this can cause a dangerous drop in blood pressure.
- It should be used with caution in patients with cardiovascular disease, severe liver impairment, severe kidney impairment, or retinitis pigmentosa.
- It is important to inform the healthcare provider about all medications, including over-the-counter drugs and herbal supplements, as they may interact with vardenafil.
Consultation with Healthcare Professional:
- The use of VALIF-20 should be discussed with a qualified healthcare professional, typically a urologist or primary care physician.
- A thorough medical evaluation should be conducted to determine the underlying cause of erectile dysfunction and to discuss potential risks and benefits before starting VALIF-20 therapy.
VALIF-20 (Vardenafil 20 mg Tablets) by Ajanta Pharma is a highly effective treatment for erectile dysfunction, providing reliable improvement in erectile function for men. Its use involves careful adherence to dosage and administration guidelines to ensure maximum efficacy and safety.
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