Buy Virso : Sofosbuvir 400 mg Tablets Online

$95.34

Brand Name : Virso
International Trade Name : Sovaldi
Composition : Sofosbuvir
Manufactured by : Strides Arcolab Ltd.
Strength : 400 mg
Form : Tablets
Packing : Pack of 28 Tablets

Prescription Required *

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SKU: 594568 Category:

Description

Overview: Virso is a medication manufactured by Strides Arcolab Ltd. containing the active substance Sofosbuvir. It is a potent antiviral agent used in the treatment of chronic hepatitis C virus (HCV) infection. Sofosbuvir is a direct-acting antiviral (DAA) medication that targets specific proteins essential for the replication of the hepatitis C virus, thereby inhibiting its ability to multiply and spread within the body.

Active Substance:

  • Sofosbuvir: Virso contains Sofosbuvir, which is a nucleotide analogue inhibitor of the HCV NS5B RNA-dependent RNA polymerase. Sofosbuvir works by interfering with the replication process of the hepatitis C virus, inhibiting the synthesis of viral RNA strands and preventing the production of new virus particles. This ultimately leads to a reduction in viral load and may result in sustained virologic response (SVR), indicating a cure for hepatitis C infection.

Indications: Virso (Sofosbuvir) 400 mg Tablets are indicated for the treatment of:

  1. Chronic Hepatitis C Virus (HCV) Infection: It is used in combination with other antiviral medications (such as ribavirin, peginterferon, or other DAAs) for the treatment of chronic HCV infection in adults and pediatric patients aged 12 years and older. Sofosbuvir-based regimens are effective against various genotypes of HCV, including genotype 1, 2, 3, 4, 5, or 6.

Mechanism of Action: Sofosbuvir exerts its antiviral effects by several mechanisms:

  • Inhibition of NS5B RNA Polymerase: Sofosbuvir is phosphorylated intracellularly to form the active metabolite, which acts as a substrate for the HCV NS5B RNA-dependent RNA polymerase. By incorporating into the growing RNA strand during viral replication, Sofosbuvir terminates RNA synthesis and prevents the production of functional viral RNA molecules.
  • Chain Termination: Sofosbuvir acts as a nucleotide analogue, leading to premature termination of the RNA strand and inhibiting further elongation by the viral polymerase.
  • Viral Clearance: By inhibiting HCV replication, Sofosbuvir reduces viral load in the bloodstream and liver, allowing the immune system to clear the virus from the body over time.

Dosage and Administration: The dosage of Virso (Sofosbuvir) 400 mg Tablets is determined by the prescribing healthcare provider based on factors such as the patient’s genotype of HCV, liver function, previous treatment history, and concomitant medications. It is typically administered orally once daily, with or without food. The tablets should be swallowed whole with a glass of water and should not be crushed, chewed, or split. The duration of treatment may vary depending on the specific HCV genotype and treatment regimen being used.

Potential Side Effects: Common side effects associated with Virso may include:

  • Fatigue or weakness
  • Headache
  • Nausea or vomiting
  • Insomnia
  • Diarrhea
  • Rash or skin reactions
  • Decreased appetite
  • Elevated liver enzymes

Precautions:

  • Virso should be used with caution in patients with a history of liver disease, renal impairment, or co-infection with human immunodeficiency virus (HIV).
  • Patients should be monitored regularly during treatment with Sofosbuvir for signs of hepatotoxicity, renal dysfunction, or exacerbation of underlying medical conditions.
  • Virso may interact with certain medications, including rifampin, rifabutin, carbamazepine, phenytoin, and St. John’s Wort, potentially reducing the efficacy of Sofosbuvir or increasing the risk of adverse effects.

In conclusion, Virso (Sofosbuvir) 400 mg Tablets manufactured by Strides Arcolab Ltd. are a highly effective treatment option for chronic hepatitis C virus (HCV) infection. By targeting specific viral proteins essential for replication, Sofosbuvir offers a potent antiviral therapy that can lead to viral clearance and improved clinical outcomes in patients with HCV infection. However, it may cause side effects and should be used under medical supervision.

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