Description
Vivjoa (oteseconazole) Description
Vivjoa (oteseconazole) is a prescription antifungal medication used to prevent recurrent vulvovaginal candidiasis (RVVC) in females with a history of RVVC who are not of reproductive potential. RVVC is a condition in which women experience four or more episodes of vulvovaginal candidiasis (VVC) within a 12-month period.
Vivjoa (oteseconazole) Uses
Vivjoa is taken once a day for 12 months to help prevent RVVC. It is important to note that Vivjoa is not a cure for VVC, and it is not effective in treating an active VVC infection.
Vivjoa (oteseconazole) Storage Conditions
Vivjoa should be stored at room temperature (68°F to 77°F [20°C to 25°C]) and protected from light.
Vivjoa (oteseconazole) Mechanism of Action
Vivjoa is a highly selective inhibitor of fungal CYP51, which is an enzyme that is essential for the synthesis of ergosterol, a key component of fungal cell membranes. By inhibiting CYP51, Vivjoa prevents the formation of ergosterol, which weakens the fungal cell membrane and ultimately leads to cell death.
Vivjoa (oteseconazole) How to Use
Vivjoa should be taken once a day with food. The capsules should be swallowed whole and not chewed, crushed, dissolved, or opened.
Vivjoa (oteseconazole) Precautions
Vivjoa is contraindicated in females of reproductive potential and in pregnant and lactating women. Vivjoa may cause fetal harm, and the drug exposure window of approximately 690 days (based on 5 times the half-life of oteseconazole) precludes adequate mitigation of the embryo-fetal toxicity risks.
Vivjoa should be used with caution in patients with liver disease, as it can cause elevated liver enzymes. Vivjoa should also be used with caution in patients who are taking other medications that are metabolized by the liver, as it may increase the levels of these medications in the blood.
Vivjoa (oteseconazole) Drug Interactions
Vivjoa can interact with other medications that are metabolized by the liver. This includes medications such as statins, oral contraceptives, and some antidepressants. If you are taking any other medications, be sure to tell your doctor before starting Vivjoa.
Vivjoa (oteseconazole) Contraindications
Vivjoa is contraindicated in:
- Females of reproductive potential
- Pregnant women
- Lactating women
- Patients with a history of hypersensitivity to oteseconazole or other azole antifungal medications
Vivjoa (oteseconazole) Overdose
There is no known specific antidote for Vivjoa overdose. In the event of an overdose, supportive care should be provided.
Vivjoa (oteseconazole) Adverse Reactions
The most common adverse reactions associated with Vivjoa are headache, nausea, and vaginal discharge. Other adverse reactions that may occur include:
- Abdominal pain
- Diarrhea
- Fatigue
- Hot flashes
- Menstrual abnormalities
- Rash
- Vaginal irritation
Conclusion
Vivjoa is a safe and effective medication for the prevention of RVVC in females with a history of RVVC who are not of reproductive potential. It is important to note that Vivjoa is not a cure for VVC, and it is not effective in treating an active VVC infection. If you have any questions or concerns about Vivjoa, be sure to talk to your doctor.
Reviews
There are no reviews yet.