Description
Zegalogue (dasiglucagon) is an injectable medication used to treat severe hypoglycemia in people with diabetes aged 6 years and older. Hypoglycemia occurs when the blood sugar level drops too low, and severe hypoglycemia can lead to unconsciousness or seizures.
Uses:
Zegalogue is used to quickly raise blood sugar levels in people with diabetes who have experienced severe hypoglycemia. It is intended for use in emergency situations and is not a substitute for a patient’s regular diabetes medications.
Storage Conditions:
Zegalogue should be stored at room temperature, between 68°F and 77°F (20°C and 25°C), for up to 90 days. The medication should not be frozen or shaken.
Mechanism of Action:
Zegalogue is a synthetic form of glucagon, a hormone that raises blood sugar levels by stimulating the liver to release glucose into the bloodstream. It works by activating the glucagon receptor in the liver, which triggers the release of stored glucose into the bloodstream. This quickly raises blood sugar levels and prevents severe hypoglycemia.
HOW TO USE:
Zegalogue is administered by subcutaneous injection. The dose is based on the patient’s weight and should be determined by the healthcare provider. Patients, family members, or caregivers should be trained on how to administer the injection in an emergency situation.
Precautions:
• Zegalogue should not be used in patients with pheochromocytoma, a rare type of tumor that can cause an increase in blood pressure and heart rate.
• Patients should be monitored for signs of allergic reactions, including rash, swelling, or difficulty breathing.
• Patients who develop an allergic reaction to Zegalogue should discontinue the medication and receive appropriate medical care.
• Zegalogue should be used with caution in patients with adrenal insufficiency, as it may not be effective in these patients.
Drug Interactions:
• Zegalogue may interact with insulin or other drugs that lower blood sugar levels. Concurrent use may increase the risk of hypoglycemia.
• Patients who take drugs that increase heart rate or blood pressure, such as beta-adrenergic agonists, may experience an increase in these effects when taking Zegalogue.
Contraindications:
• Zegalogue is contraindicated in patients with pheochromocytoma.
• Zegalogue is also contraindicated in patients with a known hypersensitivity to dasiglucagon or any of its components.
Overdose:
There is limited information on the effects of overdose with Zegalogue. In case of overdose, patients should seek immediate medical attention.
Adverse Reactions:
The most common adverse reactions to Zegalogue include nausea, vomiting, headache, and injection site reactions, such as redness or swelling. Patients should notify their healthcare provider if they experience any unusual symptoms while taking Zegalogue.
In summary, Zegalogue (dasiglucagon) is an injectable medication used to quickly raise blood sugar levels in people with diabetes who have experienced severe hypoglycemia. It is intended for use in emergency situations and is not a substitute for regular diabetes medications. Zegalogue is a synthetic form of glucagon that stimulates the liver to release stored glucose, raising blood sugar levels. It is administered by subcutaneous injection and dosed based on the patient’s weight. Zegalogue should be stored at room temperature and should not be frozen or shaken. It is contraindicated in patients with pheochromocytoma or hypersensitivity to dasiglucagon or its components. Adverse reactions to the medication can include nausea, vomiting, headache, and injection site reactions. Special precautions should be taken in patients with adrenal insufficiency or those taking drugs that increase heart rate or blood pressure.
Reviews
There are no reviews yet.